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官方网页科教人文Costello,Catherine个人资料、作品Costello，Catherine个人资料，教授 主任-波士顿大学-个人资料，个人简历 AB， Emmanuel College， Boston， MAr MS， PhD， Georgetown University， Washington， DC 近期论文 Complete Post Translational Modification Mapping of Pathogenic N. meningitidis Pilins Requires Top-Down Mass Spectrometry. Gault， J.; Malosse， C.; M
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个人简历AB, Emmanuel College, Boston, MArMS, PhD, Georgetown University, Washington, DC近期论文Complete Post Translational Modification Mapping of Pathogenic N. meningitidis Pilins Requires Top-Down Mass Spectrometry. Gault, J.; Malosse, C.; Machata, S.; Millien, C.; Podglajen, I.; Ploy, M.-C.; Costello, C. E.; Duménil, G.; Chamot-Rooke, J, Proteomics, 2013, in press.rrEvidence for a structural role for acid-fast lipids in oocyst walls of Cryptosporidium, Toxoplasma, and Eimeria. Bushkin GG, Motari E, Carpentieri A, Dubey JP, Costello CE, Robbins PW, Samuelson J. MBio. 2013 Sep 3;4(5):e00387-13. doi: 10.1128/mBio.00387-13.rrMass Spectrometry of Glycans. Han, L.; Costello, C. E. Biochemistry (Moscow) 2013, 78, 710-720.rrSTRAP PTM: Software Tool for Rapid Annotation and Differential Comparison of Protein Post-Translational Modifications. Spencer, J. L.; Bhatia, V. N.; Whelan, S. A.; Costello, C. E.; McComb, M. E. Curr. Protocols Bioinf., 2013, in press.rrThe binding sites of monoclonal antibodies to the non-reducing end of Francisella tularensis O-antigen accommodate mainly the terminal saccharide.Lu Z, Rynkiewicz MJ, Yang CY, Madico G, Perkins HM, Wang Q, Costello CE, Zaia J, Seaton BA, Sharon J. Immunology. 2013 Nov;140(3):374-89. doi: 10.1111/imm.12150.rrUltraviolet laser-induced cross-linking in peptides. Leo G, Altucci C, Bourgoin-Voillard S, Gravagnuolo AM, Esposito R, Marino G, Costello CE, Velotta R, Birolo L. Rapid Commun Mass Spectrom. 2013 Jul 30;27(14):1660-8. doi: 10.1002/rcm.6610.rrThe aryl hydrocarbon receptor directs hematopoietic progenitor cell expansion and differentiation. Smith BW, Rozelle SS, Leung A, Ubellacker J, Parks A, Nah SK, French D, Gadue P, Monti S, Chui DH, Steinberg MH, Frelinger AL, Michelson AD, Theberge R, McComb ME, Costello CE, Kotton DN, Mostoslavsky G, Sherr DH, Murphy GJ. Blood. 2013 Jul 18;122(3):376-85. doi: 10.1182/blood-2012-11-466722. Epub 2013 May 30.rrEpithelial Wounds Induce Differential Phosphorylation Changes in Response to Purinergic and EGF Receptor Activation. Kehasse A, Rich CB, Lee A, McComb ME, Costello CE, Trinkaus-Randall V. Am J Pathol. 2013 Oct 1. doi:pii: S0002-9440(13)00600-7. 10.1016/j.ajpath.2013.08.015.rrDetailed Glycan Structural Characterization by Electronic Excitation Dissociation.Yu X, Jiang Y, Chen Y, Huang Y, Costello CE, Lin C. Anal Chem. 2013 Oct 9. [Epub ahead of print]rrA novel human autoantigen, endothelial cell growth factor, is a target of T and B cell responses in patients with Lyme disease. Drouin EE, Seward RJ, Strle K, McHugh G, Katchar K, Londoño D, Yao C, Costello CE, Steere AC. Arthritis Rheum. 2013 Jan;65(1):186-96.rrMass Spectrometry of Glycans. Han, L.; Costello, C. E. Biochemistry (Moscow) 2013, 78, 710-720.rrβ-1,3-glucan, which can be targeted by drugs, forms a trabecular scaffold in the oocyst walls of Toxoplasma and Eimeria. Bushkin GG, Motari E, Magnelli P, Gubbels MJ, Dubey JP, Miska KB, Bullitt E, Costello CE, Robbins PW, Samuelson J. MBio. 2012 Sep 25;3(5).rrLipid sorting by ceramide structure from plasma membrane to ER for the cholera toxin receptor ganglioside GM1. Chinnapen DJ, Hsieh WT, te Welscher YM, Saslowsky DE, Kaoutzani L, Brandsma E, D’Auria L, Park H, Wagner JS, Drake KR, Kang M, Benjamin T, Ullman MD, Costello CE, Kenworthy AK, Baumgart T, Massol RH, Lencer WI. Dev Cell. 2012 Sep 11;23(3):573-86.rrEnergy-dependent electron activated dissociation of metal-adducted permethylated oligosaccharides. Yu X, Huang Y, Lin C, Costello CE. Anal Chem. 2012 Sep 4;84(17):7487-94.rrTop-down study of β2-microglobulin deamidation. Li X, Yu X, Costello CE, Lin C, O’Connor PB. Anal Chem. 2012 Jul 17;84(14):6150-7.rrProtective B-cell epitopes of Francisella tularensis O-polysaccharide in a mouse model of respiratory tularaemia. Lu Z, Madico G, Roche MI, Wang Q, Hui JH, Perkins HM, Zaia J, Costello CE, Sharon J. Immunology. 2012 Jul;136(3):352-60.rrA typical preparation of Francisella tularensis O-antigen yields a mixture of three types of saccharides. Wang Q, Shi X, Leymarie N, Madico G, Sharon J, Costello CE, Zaia J. Biochemistry. 2011 Dec 20;50(50):10941-50.rrDetermination of Lipid Composition of the Outer Layer of Bacterial Walls: Mass-spectrometric Approach. Elkin, Y. N.; Budnik, B. A.; Ivleva, V. B.; Nazarenko, E. L.; O’Connor, H. B.; Costello, C. E. Russ. J. Mass Spectrom., 2011, 8, 273-280.rrOxidation of HRas cysteine thiols by metabolic stress prevents palmitoylation in vivo and contributes to endothelial cell apoptosis. Burgoyne JR, Haeussler DJ, Kumar V, Ji Y, Pimental DR, Zee RS, Costello CE, Lin C, McComb ME, Cohen RA, Bachschmid MM. FASEB J. 2012 Feb;26(2):832-41.rrElectron transfer dissociation of milk oligosaccharides. Han L, Costello CE. J Am Soc Mass Spectrom. 2011 Jun;22(6):997-1013.rrThe human proteome project: current state and future direction. Legrain P, Aebersold R, Archakov A, Bairoch A, Bala K, Beretta L, Bergeron J, Borchers CH, Corthals GL, Costello CE, Deutsch EW, Domon B, Hancock W, He F, Hochstrasser D, Marko-Varga G, Salekdeh GH, Sechi S, Snyder M, Srivastava S, Uhlén M, Wu CH, Yamamoto T, Paik YK, Omenn GS. Mol Cell Proteomics. 2011 Jul;10(7):M111.rrTop-Down Analysis of Small Plasma Proteins Using an LTQ-Orbitrap. Potential for Mass Spectrometry-Based Clinical Assays for Transthyretin and Hemoglobin. Théberge R, Infusini G, Tong W, McComb ME, Costello CE. Int J Mass Spectrom. 2011 Mar 1;300(2-3):130-142.rrChymotrypsin C is a co-activator of human pancreatic procarboxypeptidases A1 and A2. Szmola R, Bence M, Carpentieri A, Szabó A, Costello CE, Samuelson J, Sahin-Tóth M. J Biol Chem. 2011 Jan 21;286(3):1819-27. doi: 10.1074/jbc.M110.187369. Epub 2010 Nov 22rrSeward, R. J.; Drouin, E. E.; Steere, A. C.; Costello, C. E. Peptides Presented by HLA-DR Molecules in Synovia of Patients with Rheumatoid Arthritis or Antibiotic-Refractory Lyme Arthritis. Mol Cell Proteomics2011, 10, M110 002477. Pubmed LinkrrZee, R. S.; Yoo, C. B.; Pimentel, D. R.; Perlman, D. H.; Burgoyne, J. R.; Hou, X.; McComb, M. E.; Costello, C. E.; Cohen, R. A.; Bachschmid, M. M. Redox regulation of sirtuin-1 by S-glutathiolation. Antioxidants & redox signaling2010, 13, 1023-32. Pubmed LinkrrThe antiretroviral lectin cyanovirin-N targets well-known and novel targets on the surface of Entamoeba histolytica trophozoites. Carpentieri A, Ratner DM, Ghosh SK, Banerjee S, Bushkin GG, Cui J, Lubrano M, Steffen M,Costello CE, O’Keefe B, Robbins PW, Samuelson J. Eukaryot Cell. 2010 Nov;9(11):1661-8.rrPeptides presented by HLA-DR molecules in synovia of patients with rheumatoid arthritis or antibiotic-refractory Lyme arthritis.Seward RJ, Drouin EE, Steere AC, Costello CE. Mol Cell Proteomics. 2011 Mar;10(3):M110.002477.rrDetermination of Lipid Composition of the Outer Layer of Bacterial Walls: Mass-spectrometric Approach. Elkin, Y. N.; Budnik, B. A.; Ivleva, V. B.; Nazarenko, E. L.; O’Connor, H. B.; Costello, C. E. Russ. J. Mass Spectrom., 2011, 8, 273-280.rrWada, Y.; Dell, A.; Haslam, S. M.; Tissot, B.; Canis, K.; Azadi, P.; Backstrom, M.; Costello, C. E.; Hansson, G. C.; Hiki, Y.; Ishihara, M.; Ito, H.; Kakehi, K.; Karlsson, N.; Kato, K.; Kawasaki, N.; Khoo, K. H.; Kobayashi, K.; Kolarich, D.; Kondo, A.; Lebrilla, C.; Nakano, M.; Narimatsu, H.; Novak, J.; Novotny, M. V.; Ohno, E.; Packer, N. H.; Renfrow, M. B.; Tajiri, M.; Thomsson, K. A.; Yagi, H.; Yu, S. Y.; Taniguchi, N. Comparison of Methods for Profiling O-glycosylation: HUPO Human Disease Glycomics/Proteome Initiative Multi-Institutional Study of IgA1. Mol Cell Proteomics2010, 9, 719-727. Pubmed LinkrrStaples, G. O.; Naimy, H.; Yin, H.; Kileen, K.; Kraiczek, K.; Costello, C. E.; Zaia, J. Improved hydrophilic interaction chromatography LC/MS of heparinoids using a chip with postcolumn makeup flow. Anal. Chem.2010, 82, 516-22. Pubmed LinkrrRole of glycosaminoglycan sulfation in the formation of immunoglobulin light chain amyloid oligomers and fibrils.Ren R, Hong Z, Gong H, Laporte K, Skinner M, Seldin DC, Costello CE, Connors LH, Trinkaus-Randall V. J Biol Chem. 2010 Nov 26;285(48):37672-82. doi: 10.1074/jbc.M110.149575. Epub 2010 Sep 24.rrPalaima, E.; Leymarie, N.; Stroud, D.; Mizanur, R. M.; Hodgkin, J.; Gravato-Nobre, M. J.; Costello, C. E.; Cipollo, J. F. The Caenorhabditis elegans bus-2 mutant reveals a new class of O-glycans affecting bacterial resistance. J Biol Chem2010, 285, 17662-72. Pubmed LinkrrLi, X.; Lin, C.; Han, L.; Costello, C. E.; O’Connor, P. B. Charge remote fragmentation in electron capture and electron transfer dissociation. J Am Soc Mass Spectrom2010, 21, 646-56. Pubmed LinkrrEbbel, E. N.; Leymarie, N.; Schiavo, S.; Sharma, S.; Gevorkian, S.; Hersch, S.; Matson, W. R.; Costello, C. E. Identification of phenylbutyrate-generated metabolites in Huntington disease patients using parallel liquid chromatography/electrochemical array/mass spectrometry and off-line tandem mass spectrometry. Anal Biochem2010, 399, 152-61. Pubmed LinkrrNaimy, H.; Staples, G. O.; McComb, M.; Costello, C. E., J. Zaia, J.; Leymarie, N. Patterns of Tissue-Specific Glycosaminoglycan Expression Revealed by Tandem Mass Spectrometry and Statistical Methods. J. Biomol. Tech. 2010, 21(3 Suppl): S24–S25.rrChatterjee, A.; Carpentieri, A.; Ratner, D. M.; Bullitt, E.; Costello, C. E.; Robbins, P. W.; Samuelson, J. Giardia cyst wall protein 1 is a lectin that binds to curled fibrils of the GalNAc homopolymer. PLoS Pathog2010, 6, e1001059. Pubmed LinkrrCarpentieri, A.; Ratner, D. M.; Ghosh, S. K.; Banerjee, S.; Bushkin, G. G.; Cui, J.; Lubrano, M.; Steffen, M.; Costello, C. E.; O’Keefe, B.; Robbins, P. W.; Samuelson, J. The anti-retroviral lectin cyanovirin-N targets well-known and novel targets on the surface of Entamoeba histolytica trophozoites. Eukaryot Cell2010, 9, 1661-1668. Pubmed LinkrrYoung, D. C.; Kasmar, A.; Moraski, G.; Cheng, T. Y.; Waltz, A. J.; Hu, J.; Xu, X.; Endres, G. W.; Uzieblo, A.; Zajonc, D.; Costello, C. E.; Miller, M. J.; Moody, D. B. Synthesis of dideoxymycobactin antigens presented by CD1A reveals T cell fine specificity for natural lipopeptide structures. J Biol Chem2009, 284, 25087-25096. Pubmed LinkrrYing, W.; Perlman, D. H.; Li, L.; Theberge, R.; Costello, C. E.; McComb, M. E. Highly efficient and selective enrichment of peptide subsets combining fluorous chemistry with reversed-phase chromatography. Rapid Commun Mass Spectrom2009, 23, 4019-30. Pubmed LinkrrWang, Y.; Meriin, A. B.; Zaarur, N.; Romanova, N. V.; Chernoff, Y. O.; Costello, C. E.; Sherman, M. Y. Abnormal proteins can form aggresome in yeast: aggresome-targeting signals and components of the machinery. FASEB J2009, 23, 451-63. Pubmed LinkrrStaples, G.; Bowman, M.; Costello, C. E.; Hitchcock, A.; Lau, J.; Leymarie, N.; Miller, C.; Naimy, H.; Shi, X.; Zaia, J. A Chip-based Amide-HILIC LC/MS Platform for Glycosaminoglycan Glycomics. Proteomics2009, 9, 686-695. Pubmed LinkrrSingh, B. N.; Hayes, G. R.; Lucas, J. J.; Sommer, U.; Viseux, N.; Mirgorodskaya, E.; Trifonova, R. T.; Sassi, R. R.; Costello, C. E.; Fichorova, R. N. Structural details and composition of Trichomonas vaginalis lipophosphoglycan in relevance to the epithelial immune function. Glycoconj J2009, 26, 3-17. Pubmed LinkrrRomesser, P. B.; Perlman, D. H.; Faller, D. V.; Costello, C. E.; McComb, M. E.; Denis, G. V. Development of a malignancy-associated proteomic signature for diffuse large B-cell lymphoma. The American journal of pathology2009, 175, 25-35. Pubmed LinkrrRex, S.; Beaulieu, L. M.; Perlman, D. H.; Vitseva, O.; Blair, P. S.; McComb, M. E.; Costello, C. E.; Freedman, J. E. Immune versus thrombotic stimulation of platelets differentially regulates signalling pathways, intracellular protein-protein interactions, and alpha-granule release. Thromb Haemost2009, 102, 97-110. Pubmed LinkrrPerlman, D. H.; Bauer, S. M.; Ashrafian, H.; Bryan, N. S.; Garcia-Saura, M. F.; Lim, C. C.; Fernandez, B. O.; Infusini, G.; McComb, M. E.; Costello, C. E.; Feelisch, M. Mechanistic insights into nitrite-induced cardioprotection using an integrated metabolomic/proteomic approach. Circ Res2009, 104, 796-804. Pubmed LinkMakkinje, A.; Near, R. I.; Infusini, G.; Vanden Borre, P.; Bloom, A.; Cai, D.; Costello, C. E.; Lerner, A. AND-34/BCAR3 regulates adhesion-dependent p130Cas serine phosphorylation and breast cancer cell growth pattern. Cell Signal2009, 21, 1423-35. Pubmed Link
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