官方网页 科教人文：Allen,Karen
官方网页科教人文Allen,Karen个人资料、作品Allen，Karen个人资料，教授-波士顿大学-个人资料，个人简历 B.S.， cum laude in Biology， Tufts University， 1984 Ph.D. in Biochemistry， Brandeis University， 1989 American Cancer Society Postdoctoral Fellow in X-ray Crystallography， Massachusetts Institute of Technology， 1989 and Brandeis University， 199
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个人简历B.S., cum laude in Biology, Tufts University, 1984Ph.D. in Biochemistry, Brandeis University, 1989American Cancer Society Postdoctoral Fellow in X-ray Crystallography, Massachusetts Institute of Technology, 1989 and Brandeis University, 1990近期论文Lanthanide-tagged proteins–an illuminating partnership.rrAllen KN, Imperiali B.rrCurr Opin Chem Biol. 2010 Apr;14(2):247-54. Epub 2010 Jan 25.PMID: 20102793 [PubMed – in process]rrChirality holds the key for potent inhibition of the botulinum neurotoxin serotype a protease.rrStowe GN, Silhár P, Hixon MS, Silvaggi NR, Allen KN, Moe ST, Jacobson AR, Barbieri JT, Janda KD.rrOrg Lett. 2010 Feb 19;12(4):756-9.PMID: 20092262 [PubMed – indexed for MEDLINE]rrDivergence of biochemical function in the HAD superfamily: D-glycero-D-manno-heptose-1,7-bisphosphate phosphatase (GmhB).rrWang L, Huang H, Nguyen HH, Allen KN, Mariano PS, Dunaway-Mariano D.rrBiochemistry. 2010 Feb 16;49(6):1072-81.PMID: 20050615 [PubMed – indexed for MEDLINE]rrStructural determinants of substrate recognition in the HAD superfamily member D-glycero-D-manno-heptose-1,7-bisphosphate phosphatase (GmhB) .rrNguyen HH, Wang L, Huang H, Peisach E, Dunaway-Mariano D, Allen KN.rrBiochemistry. 2010 Feb 16;49(6):1082-92.PMID: 20050614 [PubMed – indexed for MEDLINE]rrMarkers of fitness in a successful enzyme superfamily.rrAllen KN, Dunaway-Mariano D.rrCurr Opin Struct Biol. 2009 Dec;19(6):658-65. Epub 2009 Nov 2. Review.PMID: 19889535 [PubMed – indexed for MEDLINE]rrThe origin of the electrostatic perturbation in acetoacetate decarboxylase.rrHo MC, Ménétret JF, Tsuruta H, Allen KN.rrNature. 2009 May 21;459(7245):393-7.PMID: 19458715 [PubMed – indexed for MEDLINE]rrAnalysis of the structural determinants underlying discrimination between substrate and solvent in beta-phosphoglucomutase catalysis.rrDai J, Finci L, Zhang C, Lahiri S, Zhang G, Peisach E, Allen KN, Dunaway-Mariano D.rrBiochemistry. 2009 Mar 10;48(9):1984-95.PMID: 19154134 [PubMed – indexed for MEDLINE]rrStructure-function analysis of 2-keto-3-deoxy-D-glycero-D-galactonononate-9-phosphate phosphatase defines specificity elements in type C0 haloalkanoate dehalogenase family members.rrLu Z, Wang L, Dunaway-Mariano D, Allen KN.rrJ Biol Chem. 2009 Jan 9;284(2):1224-33. Epub 2008 Nov 5.PMID: 18986982 [PubMed – indexed for MEDLINE]rrHuman symbiont Bacteroides thetaiotaomicron synthesizes 2-keto-3-deoxy-D-glycero-D- galacto-nononic acid (KDN).rrWang L, Lu Z, Allen KN, Mariano PS, Dunaway-Mariano D.rrChem Biol. 2008 Sep 22;15(9):893-7.PMID: 18804026 [PubMed – indexed for MEDLINE]rrCatalytic features of the botulinum neurotoxin A light chain revealed by high resolution structure of an inhibitory peptide complex.rrSilvaggi NR, Wilson D, Tzipori S, Allen KN.rrBiochemistry. 2008 May 27;47(21):5736-45. Epub 2008 May 6.PMID: 18457419 [PubMed – indexed for MEDLINE]rrThe catalytic scaffold of the haloalkanoic acid dehalogenase enzyme superfamily acts as a mold for the trigonal bipyramidal transition state.rrLu Z, Dunaway-Mariano D, Allen KN.Proc Natl Acad Sci U S A. 2008 Apr 15;105(15):5687-92. Epub 2008 Apr 8.PMID: 18398008 [PubMed – indexed for MEDLINE]
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